MOTS-c

What Is MOTS-c?
Overview:
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-derived peptide that plays a crucial role in regulating metabolism, energy production, and cellular stress response. Discovered in 2015, MOTS-c is naturally produced in the mitochondria and helps optimize glucose utilization, enhance fat metabolism, and support cellular resilience, making it a promising agent for anti-aging, performance enhancement, and metabolic health.

How It Works:
Mitochondrial Signaling: Acts as a hormone-like messenger, improving mitochondrial function and cellular energy efficiency
Metabolic Regulation: Enhances insulin sensitivity and supports glucose uptake in muscle tissue
AMPK Activation: Triggers AMPK (AMP-activated protein kinase), a key energy sensor that promotes fat oxidation and cellular repair
Exercise Mimetic: Mimics the effects of physical activity at the molecular level, improving endurance and metabolic flexibility
Stress Resistance: Increases resilience to oxidative and metabolic stress

Benefits of MOTS-c:
Improves insulin sensitivity and glucose metabolism
Enhances fat loss, lean muscle preservation, and metabolic flexibility
Supports mitochondrial health and cellular energy
Increases exercise endurance and recovery
May contribute to anti-aging and longevity by protecting against age-related metabolic decline
Shows potential for managing obesity, type 2 diabetes, and inflammation