Mitochondrial-derived peptide
MOTS-c
Mostly animal researchA peptide encoded in mitochondrial DNA, studied for its role in metabolism.
Evidence
Mostly animal research
Regulatory status
Not FDA-approved.
Class
Mitochondrial-derived peptide
What it is
MOTS-c is a short peptide encoded within mitochondrial DNA. Researchers describe it as a signal that helps regulate metabolism, especially in muscle.
What the research shows
- Animal studies have explored insulin sensitivity, exercise capacity, and age-related metabolic decline.
- Human research is at a very early stage.
Read the published research on PubMed →
Researched for
MOTS-c is not FDA-approved for the uses people commonly discuss. Its safety and effectiveness in people have not been established. Talk to a licensed provider before making any decision.
Educational content, not medical advice. This page does not recommend or dose any substance.
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